Geriatric Nutritional Risk Index, a simplified nutritional screening index, is a significant predictor of mortality in chronic dialysis patients<\/h1>\n
Ikue Kobayashi, Eiji Ishimura, Yoko Kato, Senji Okuno, Tadashi Yamamoto, Tomoyuki Yamakawa, Katsuhito Mori, Masaaki Inaba and Yoshiki Nishizawa<\/p>\n
Nephrol Dial Transplant (2010) 25: 3361-3365<\/a><\/p>\n

Abstract<\/h2>\n
Background<\/h3>\n
Malnutrition is a common complication in haemodialysis patients. Recently, the Geriatric Nutritional Risk Index (GNRI) has been reported as a simple and accurate tool to assess nutritional status of haemodialysis patients. Our objective was to examine the association between GNRI and mortality in chronic haemodialysis patients.<\/p>\n
Methods<\/h3>\n
We examined the GNRI of 490 maintenance haemodialysis patients (60 \u00b1 12 years, 293 males and 197 females) and followed up these patients for 60 months. Predictors for all-cause death were examined using Kaplan\u2013Meier analysis and Cox proportional analyses.<\/p>\n
Results<\/h3>\n
The GNRI was 98.0 \u00b1 6.0, and was significantly and negatively correlated with age and haemodialysis duration. During the 60-month follow-up period, 129 patients died. According to the highest positive likelihood and risk ratios, the cutoff value of GNRI for mortality was set at 90. Kaplan\u2013Meier analysis revealed that patients with a GNRI <90 (n = 50) had a significantly lower survival rate, compared to those with GNRI \u226590 (n = 440) (log-rank test, P < 0.0001). Multivariate Cox proportional hazards analyses demonstrated that GNRI was a significant predictor for mortality [hazard ratio (HR) 0.962, 95% confidence interval (CI) 0.931\u20130.995, P < 0.05], after adjustment for age, gender, C-reactive protein, presence of diabetes and haemodialysis duration.<\/p>\n
Conclusions<\/h3>\n
These results demonstrated that GNRI is a significant predictor for mortality in haemodialysis patients. The simple method of GNRI is considered to be a clinically useful marker for the assessment of nutritional status in haemodialysis patients. <\/p>\n
Keywords: Geriatric Nutritional Risk Index; haemodialysis; malnutrition; mortality<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"
Zadeh has reported that malnutrition-Inflammation Score (MIS) is predictor of mortality in hemodialysis patien … “Geriatric Nutritional Risk Index, a simplified nutritional screening index, is a significant predictor of mortality in chronic dialysis patients” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":6029,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[11,4],"tags":[169,150,170,171],"class_list":["post-2409","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-healthcare","category-nutrition","tag-geriatric-nutritional-risk-index","tag-haemodialysis","tag-malnutrition","tag-mortality"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t