{"id":4731,"date":"2014-01-19T18:00:37","date_gmt":"2014-01-19T09:00:37","guid":{"rendered":"http:\/\/fujiitoshiki.com\/improvesociety\/?p=4731"},"modified":"2017-04-27T16:12:48","modified_gmt":"2017-04-27T07:12:48","slug":"systemic-igg4-related-lymphadenopathy-a-clinical-and-pathologic-comparison-to-multicentric-castlemans-disease","status":"publish","type":"post","link":"https:\/\/www.fujiitoshiki.com\/improvesociety\/?p=4731","title":{"rendered":"Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman&#8217;s disease"},"content":{"rendered":"<div class=\"theContentWrap-ccc\"><p>\u3000\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u3068 systemic IgG4-related lymphadenopathy \u3068\u306e\u9451\u5225\u70b9\u306b\u3064\u3044\u3066\u8ff0\u3079\u3089\u308c\u3066\u3044\u307e\u3059\uff0eSystemic IgG4-related lymphadenopathy \u306e\u4e00\u90e8\u3068\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u3068\u3067\u306f\u75c5\u7406\u50cf\u306b\u5171\u901a\u70b9\u3082\u898b\u3089\u308c\u307e\u3059\u304c\uff0cCRP \u3068 IL-6 \u306b\u3088\u308a\u9451\u5225\u3067\u304d\u308b\u3068\u3057\u3066\u3044\u307e\u3059\uff0e<\/p>\n<p><iframe loading=\"lazy\" frameborder=\"0\" allowtransparency=\"true\" height=\"60\" width=\"468\" marginheight=\"0\" scrolling=\"no\" src=\"\/\/ad.jp.ap.valuecommerce.com\/servlet\/htmlbanner?sid=2990468&#038;pid=882858595\" marginwidth=\"0\"><script language=\"javascript\" src=\"\/\/ad.jp.ap.valuecommerce.com\/servlet\/jsbanner?sid=2990468&#038;pid=882858595\"><\/script><noscript><a href=\"\/\/ck.jp.ap.valuecommerce.com\/servlet\/referral?sid=2990468&#038;pid=882858595\" target=\"_blank\" ><img loading=\"lazy\" decoding=\"async\" src=\"\/\/ad.jp.ap.valuecommerce.com\/servlet\/gifbanner?sid=2990468&#038;pid=882858595\" height=\"60\" width=\"468\" border=\"0\"><\/a><\/noscript><\/iframe><\/p>\n<h1>Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman&#8217;s disease<\/h1>\n<p>Yasuharu Sato, Masaru Kojima, Katsuyoshi Takata, Toshiaki Morito, Hideki Asaoku, Tamotsu Takeuchi, Kohichi Mizobuchi, Megumu Fujihara, Kazuya Kuraoka, Tokiko Nakai, Kouichi Ichimura, Takehiro Tanaka, Maiko Tamura, Yuriko Nishikawa and Tadashi Yoshino<\/p>\n<p><a href=\"\/\/www.nature.com\/modpathol\/journal\/v22\/n4\/full\/modpathol200917a.html\" title=\"Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman's disease\" target=\"_blank\">Modern Pathology (2009) 22, 589\u2013599<\/a><\/p>\n<p>IgG4 \u95a2\u9023\u75be\u60a3\u306f\u6642\u306b\u5c40\u6240\u307e\u305f\u306f\u5168\u8eab\u30ea\u30f3\u30d1\u7bc0\u306b\u6d78\u6f64\u3057\uff0c\u6642\u306b\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u3084\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u3068\u81e8\u5e8a\u7684\u30fb\u7d44\u7e54\u5b66\u7684\u306b\u985e\u4f3c\u3059\u308b\uff0e\u672c\u7814\u7a76\u3067\u306f\u6211\u3005\u306f systemic IgG4-related lymphadenopathy \u306e\u81e8\u5e8a\u7684\u30fb\u75c5\u7406\u5b66\u7684\u6240\u898b\u3092\u8abf\u67fb\u3057\u305f\uff0e\u30d2\u30c8\u30d8\u30eb\u30da\u30b9\u30a6\u30a4\u30eb\u30b9 8 \u3084 HIV \u611f\u67d3\u3068\u95a2\u9023\u3057\u305f\u75c7\u4f8b\u3084\uff0cT cell receptor \u3084\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u306e\u907a\u4f1d\u5b50\u518d\u69cb\u6210\u3068\u95a2\u9023\u3057\u305f\u75c7\u4f8b\u306f\u306a\u304b\u3063\u305f\uff0e\u7d44\u7e54\u5b66\u7684\u306b\u306f systemic IgG4-related lymphadenopathy \u306f IgG4 \u967d\u6027\u7d30\u80de\u306e\u6d78\u6f64\u30d1\u30bf\u30fc\u30f3\u306b\u3088\u308a 2 \u578b\u306b\u5206\u985e\u3055\u308c\u308b\uff0e\u3059\u306a\u308f\u3061\uff0c\u6ffe\u80de\u9593\u5f62\u8cea\u7d30\u80de\u578b\u3068\u80da\u4e2d\u5fc3\u5f62\u8cea\u7d30\u80de\u578b\u306b\uff0e\u6ffe\u80de\u9593\u5f62\u8cea\u7d30\u80de\u578b\u306f\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u69d8\u304b\u7570\u578b\u30ea\u30f3\u30d1\u5f62\u8cea\u7d30\u80de\u306e\u50cf\u3092\u5448\u3057\uff0c\u514d\u75ab\u82bd\u7d30\u80de\u5897\u6b96\u69d8\u306e\u7279\u5fb4\u3092\u5448\u3059\u308b\uff0e\u5bfe\u7167\u7684\u306b\uff0c\u80da\u4e2d\u5fc3\u5f62\u8cea\u7d30\u80de\u578b\u306f\u8457\u660e\u306a\u6ffe\u80de\u306e\u904e\u5f62\u6210\u3092\u5448\u3057\uff0cIgG4 \u967d\u6027\u7d30\u80de\u306f\u4e3b\u306b\u80da\u4e2d\u5fc3\u306b\u6d78\u6f64\u3057\uff0c\u3042\u308b\u4f8b\u3067\u306f\u9032\u884c\u3057\u305f\u80da\u4e2d\u5fc3\u306e\u5f62\u8cea\u8ee2\u63db\u50cf\u3092\u5448\u3057\u3066\u3044\u305f\uff0e\u8208\u5473\u6df1\u3044\u3053\u3068\u306b 9 \u4f8b\u306e\u3046\u3061 8 \u4f8b\u3067\u597d\u9178\u7403\u6d78\u6f64\u3092\u5e79\u90e8\u306e\u30ea\u30f3\u30d1\u7bc0\u306b\u8a8d\u3081\uff0c\u8840\u6e05 IgE \u306e\u8457\u660e\u306a\u4e0a\u6607\u3092\u8a8d\u3081\u305f\uff0e\u691c\u67fb\u6240\u898b\u3067\u306f\u8840\u6e05 IgG4 \u3068 sIL-2R \u306e\u4e0a\u6607\u304c\u8a8d\u3081\u3089\u308c\u305f\uff0e\u3057\u304b\u3057\u306a\u304c\u3089\u5168\u75c7\u4f8b\u306b\u304a\u3044\u3066 IL-6, CRP, LDH \u306e\u30ec\u30d9\u30eb\u306f\u6b63\u5e38\u7bc4\u56f2\u307e\u305f\u306f\u8efd\u5ea6\u306e\u4e0a\u6607\u306b\u7559\u307e\u3063\u305f\uff0e1 \u540d\u306e\u60a3\u8005\u306f IL-6 \u306e\u9ad8\u5024\u3092\u8a8d\u3081\u305f\u304c CRP \u306f\u6b63\u5e38\u7bc4\u56f2\u306b\u7559\u307e\u3063\u305f\uff0e\u81ea\u5df1\u6297\u4f53\u3092 5 \u540d\u306e\u60a3\u8005\u3067\u691c\u67fb\u3057 4 \u540d\u306e\u60a3\u8005\u3067\u691c\u51fa\u3057\u305f\uff0e\u3053\u308c\u307e\u3067\u5831\u544a\u3055\u308c\u305f\u591a\u4e2d\u5fc3\u6027\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u306e\u75c7\u4f8b\u3068\u6bd4\u8f03\u3057\u3066\uff0c\u6211\u3005\u306e systemic IgG4-related lymphadenopathy \u306e\u60a3\u8005\u306f\u8457\u660e\u306b\u9ad8\u9f62\u3067 CRP \u3068 IL-6 \u5024\u304c\u8457\u660e\u306b\u4f4e\u5024\u3067\u3042\u3063\u305f\uff0e\u7d50\u8ad6\u3068\u3057\u3066\u6211\u3005\u306e systemic IgG4-related lymphadenopathy \u306f\uff0c\u591a\u4e2d\u5fc3\u6027\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u3068\u306e\u9593\u306b\u90e8\u5206\u7684\u306b\u5171\u901a\u3059\u308b\u75c5\u7406\u5b66\u7684\u7279\u5fb4\u3092\u6709\u3057\uff0c\u8840\u6e05\u30c7\u30fc\u30bf\uff08\u7279\u306b CRP \u3068 IL-6\uff09\u306f\u4e21\u8005\u3092\u9451\u5225\u3059\u308b\u306e\u306b\u6709\u7528\u3067\u3042\u3063\u305f\uff0e\u6211\u3005\u306e\u6240\u898b\u306f\u60a3\u90e8\u7d44\u7e54\u3078\u306e\u597d\u9178\u7403\u6d78\u6f64\u3068\u8840\u6e05 IgE \u4e0a\u6607\u3067\u3042\u308b\u304c\uff0csystemic IgG4-related lymphadenopathy \u306e\u75c5\u539f\u6027\u306b\u304a\u3044\u3066\u30a2\u30ec\u30eb\u30ae\u30fc\u7684\u306a\u6a5f\u5e8f\u3092\u793a\u5506\u3059\u308b\u306e\u304b\u3082\u3057\u308c\u306a\u3044\uff0e<\/p>\n<p>Keywords: systemic IgG4-related lymphadenopathy; C-reactive protein; interleukin-6; immunoglobulin E; multicentric castleman\u2019s disease<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u3000\u30ad\u30e3\u30c3\u30b9\u30eb\u30de\u30f3\u75c5\u3068 systemic IgG4-related lymphadenopathy \u3068\u306e\u9451\u5225\u70b9\u306b\u3064\u3044\u3066\u8ff0\u3079\u3089\u308c\u3066\u3044\u307e\u3059\uff0eSystemic IgG4-related lymphadenopathy \u306e\u4e00\u90e8\u3068\u30ad &hellip; <a href=\"https:\/\/www.fujiitoshiki.com\/improvesociety\/?p=4731\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman&#8217;s disease&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":6029,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[11],"tags":[508,510,509,511,507],"class_list":["post-4731","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-healthcare","tag-c-reactive-protein","tag-immunoglobulin-e","tag-interleukin-6","tag-multicentric-castlemans-disease","tag-systemic-igg4-related-lymphadenopathy"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/posts\/4731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4731"}],"version-history":[{"count":15,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/posts\/4731\/revisions"}],"predecessor-version":[{"id":7761,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/posts\/4731\/revisions\/7761"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=\/wp\/v2\/media\/6029"}],"wp:attachment":[{"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4731"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4731"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fujiitoshiki.com\/improvesociety\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}